Senescence inducers

Intervention

2 papers3 findings

  • 1 lab in 1 country
  • Funders: Berlin Institute of Health and 3 more
  • Cells1

Outcomes

3

Plasminogen activator INHIBITOR-1

downin mouse cells1

1 study
  1. Senescence inducers decrease plasminogen activator INHIBITOR-1 in mouse cells.

    “Plasminogen activator inhibitor-1 exhibited global downregulation across all modes of senescence.”

    Cellsacross all modes of senescencehepatocyte

    Delineating the heterogeneity of senescence-induced-functional alterations in hepatocytes

    Cellular and molecular life sciences : CMLS30 Apr 2024

More on Plasminogen activator INHIBITOR-1

CCL2 and IL-10

upin mouse cells1

1 study
  1. Senescence inducers increase CCL2 and IL-10 in mouse cells.

    “Among the SASP factors, CCL2 and IL-10 were consistently upregulated”

    Cellsacross senescence induction conditionshepatocyte

    Delineating the heterogeneity of senescence-induced-functional alterations in hepatocytes

    Cellular and molecular life sciences : CMLS30 Apr 2024

More on CCL2 and IL-10

Senescence marker profiles

upin mouse cells1

1 study
  1. Senescence inducers induce senescence marker profiles in mouse cells.

    “Each senescence inducer triggers a unique combination of senescence markers in hepatocytes.”

    Cellscomparison of different senescence inducershepatocyte

    Delineating the heterogeneity of senescence-induced-functional alterations in hepatocytes

    Cellular and molecular life sciences : CMLS30 Apr 2024

More on Senescence marker profiles

Latest