Across all fields, 2 papers: none in people yet, 1 in animals, 1 review
Oxidative stress and ROS signaling
downin reviews1
Selenocysteine decreases oxidative stress and ROS signaling.
“selenocysteine is incorporated into key antioxidant enzymes such as glutathione peroxidases (GPx) and thioredoxin reductases (TrxR). These molecules play pivotal roles in neutralizing ROS”
Reviewincorporated into antioxidant enzymes
Biomolecules
Reactive oxygen species
downin worms1
Selenocysteine decreases reactive oxygen species in worms.
“Selenocysteine also reduced the cellular level of reactive oxygen species known to be increased by high‐glucose‐diet.”
Model organismshigh-glucose diet
Molecular medicine reports
Survival
upin worms1
Selenocysteine increases survival in worms.
“Reduced survival caused by high‐glucose‐diet was recovered by selenocysteine.”
Model organismshigh-glucose diet
Molecular medicine reports
Amyloid-beta-induced paralysis
downin worms1
Selenocysteine decreases amyloid-beta-induced paralysis in worms.
“selenocysteine significantly delayed the paralysis induced by human amyloid‐β gene”
Model organismshuman amyloid-β gene-induced paralysis
Molecular medicine reports
Erastin and RSL3 shortened survival dose-dependently, an effect rescued by ferrostatin-1, while altering iron and lipid profiles selectively in males.Erastin and RSL3 shortened survival dose-dependently, an effect rescued by ferrostatin-1, while altering iron and lipid profiles selectively in males.