Cysteine
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16Chronic stress worsened bone loss in mice after ovary removal
In an animal experiment, mice whose ovaries had been removed showed worse osteoporosis and anxiety- and depression-like behaviour after eight weeks of…In an animal experiment, mice whose ovaries had been removed showed worse osteoporosis and anxiety- and depression-like behaviour after eight weeks of chronic stress.
Cysteine restriction extends lifespan and boosts metabolic fitness in animals
Reducing dietary cysteine independently of methionine enhanced survival in nematodes and reprogrammed the immunometabolic axis in mice.Reducing dietary cysteine independently of methionine enhanced survival in nematodes and reprogrammed the immunometabolic axis in mice.
Dietary restriction activates autophagy through selective oxidation of ATG5
Reversible oxidation of a single cysteine residue enables core autophagosome formation and prevents severe tissue pathology during nutrient limitation…Reversible oxidation of a single cysteine residue enables core autophagosome formation and prevents severe tissue pathology during nutrient limitation in mice.
Alternate-day fasting curbs liver fibrosis in mice
In mouse models, alternate-day fasting stimulated hepatocyte nitric oxide production to suppress stellate cell activation, an effect abolished by…In mouse models, alternate-day fasting stimulated hepatocyte nitric oxide production to suppress stellate cell activation, an effect abolished by hepatocyte eNOS deletion.
Arsenic triggers heart senescence in mice while quercetin counteracts the damage
Exposure to environmental arsenic caused heart dysfunction via the p53 and p21 pathway, which quercetin treatment reversed in cultured rat…Exposure to environmental arsenic caused heart dysfunction via the p53 and p21 pathway, which quercetin treatment reversed in cultured rat cardiomyoblasts.