Recombinant humanized type iii collagen

1. Recombinant humanized type iii collagen activates PI3K–AKT signalling in rat cells.

   “rhCol III bound to the integrin α2 (ITGA2) receptor on GCs and activated the PI3K/Akt signaling pathway”

   Cellsagedgranulosa cells

   Recombinant humanized type III collagen improves ovarian function via ITGA2-mediated mitochondrial function restoration in granulosa cells and extracellular matrix remodeling

   Regenerative biomaterials·28 Mar 2026

More on PI3K–AKT signalling

1. Recombinant humanized type iii collagen prevents apoptosis in rat cells.

   “thereby preventing apoptosis and cellular senescence”

   Cellsagedgranulosa cells

   Recombinant humanized type III collagen improves ovarian function via ITGA2-mediated mitochondrial function restoration in granulosa cells and extracellular matrix remodeling

   Regenerative biomaterials·28 Mar 2026

More on Apoptosis

1. Recombinant humanized type iii collagen prevents cellular senescence in rat cells.

   “supplementation of rhCol III could mitigate oxidative stress and mitochondrial dysfunction in aged granulosa cells (GCs), thereby preventing apoptosis and cellular senescence”

   Cellsagedgranulosa cells

   Recombinant humanized type III collagen improves ovarian function via ITGA2-mediated mitochondrial function restoration in granulosa cells and extracellular matrix remodeling

   Regenerative biomaterials·28 Mar 2026

More on Cellular senescence