PRODH2 knockdown
Intervention1 paper2 findings
- Animals1
Outcomes
2Strength
upin mice1
1 study
Strength
upin mice1
PRODH2 knockdown improves strength in mice.
Animalsin vivomuscle-specific knockdownskeletal muscle
Prodh2 inhibition alleviates muscle atrophy and restores strength in COPD mice · Aging cell · 1 Oct 2026
Muscle atrophy
downin mice1
1 study
Muscle atrophy
downin mice1
PRODH2 knockdown decreases muscle atrophy in mice.
Animalsin vivomuscle-specific knockdownskeletal muscle
Prodh2 inhibition alleviates muscle atrophy and restores strength in COPD mice · Aging cell · 1 Oct 2026
Latest
1Prodh2 inhibition alleviates muscle atrophy and restores strength in COPD mice
TNF-alpha triggers a mitochondrial immune pathway via Prodh2 that damages myoblasts, while silencing the enzyme restores muscle strength in mice.
Aging cell · Chen G et al.