Neighborhood disadvantage

Intervention2 papers3 findings

  • Humans2

Associations

3

Cerebrovascular reactivity

downin humans1Very low certainty

1 study
  1. Neighborhood disadvantage is associated with cerebrovascular reactivity in humans (p = 0.027).

    Humansn = 132

    Disadvantaged neighborhoods tie to lower brain vascular function · Cerebral circulation - cognition and behavior · 15 Sep 2026

Alzheimer's disease

upin humans1Low certainty

1 study
  1. Neighborhood disadvantage raises the risk of Alzheimer's disease in humans (aHR 1.25, 95% CI 1.22-1.27).

    Humansolder patients with kidney failure initiating dialysis

    Neighborhood disadvantage links to dementia in kidney failure · Kidney medicine · 20 Jul 2026

Alzheimer's disease →

Dementia

upin humans1Low certainty

1 study
  1. Neighborhood disadvantage raises the risk of dementia in humans (aHR 1.09, 95% CI 1.08-1.10).

    Humansolder patients with kidney failure initiating dialysis

    Neighborhood disadvantage links to dementia in kidney failure · Kidney medicine · 20 Jul 2026

Dementia →

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Cerebral Circulation - Cognition and BehaviorHumans

Disadvantaged neighborhoods tie to lower brain vascular function

In 132 older adults, greater neighborhood deprivation was associated with lower whole-brain cerebrovascular reactivity, independent of traditional…In 132 older adults, greater neighborhood deprivation was associated with lower whole-brain cerebrovascular reactivity, independent of traditional vascular risks and Alzheimer's pathology.

Kidney MedicineHumans

Neighborhood disadvantage links to dementia in kidney failure

Among older dialysis patients, living in highly disadvantaged neighborhoods was linked to adjusted hazard ratios of 1.09 for dementia and 1.25 for…Among older dialysis patients, living in highly disadvantaged neighborhoods was linked to adjusted hazard ratios of 1.09 for dementia and 1.25 for Alzheimer's disease.