Methotrexate

Intervention2 papers1 findingPubChem 126941ChEBI 44185

Humans1

Mouse lifespan

20220.2 ppm from 14 months+3.9% males, −0.1% females

Outcomes

1

Frailty

downin humans1

1 study

Methotrexate protects against frailty in humans.
Review
Frailty in rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis: Current evidence and knowledge gaps · Therapeutic advances in musculoskeletal disease · 22 Aug 2026

Latest

4

Clinical, Cosmetic and Investigational DermatologyResearch2 Sep

Dramatic Improvement of Treatment-Refractory Prurigo Nodularis Following Initiation of Semaglutide: A Case Report

RheumatologyHumans31 Aug

Cross-sectional stroke risk identification in RA: integrating traditional and disease-specific factors

Therapeutic Advances in Musculoskeletal DiseaseReview25 Aug

Frailty in rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis: Current evidence and knowledge gaps

Rheumatoid arthritis

AAIC 2025 AbstractHumans23 Dec

Basal Metabolic Rate, Rheumatoid Arthritis and Alzheimer’s Disease: Insights from a genetic correlation and Mendelian randomization study