Hydroxychloroquine
- 2 independent labs in 2 countries
- 3 trials, none about aging
- Funders: Kementerian Pendidikan Malaysia and 1 more
- Humans1
- Animals1
- Cells1
Outcomes
2Cell viability
downin human cells1
1 study
Cell viability
downin human cells1
Hydroxychloroquine decreases cell viability in human cells.
“inhibiting the late stage of autophagy with hydroxychloroquine (HCQ) decreased cell viability”
Cellsin Nrf2-silenced THP-1 macrophage foam cells
Nrf2 modulates macrophage foam cells senescence and autophagy activation
Toxicology mechanisms and methodsDec 3, 2025
Cell proliferation
downin human cells1
1 study
Cell proliferation
downin human cells1
Hydroxychloroquine decreases cell proliferation in human cells.
“culminating in suppressed cell proliferation”
Cellsin uric acid-treated HUVECshuman umbilical vein endothelial cells
Cell biochemistry and biophysicsSep 28, 2024
Trial sponsors
Starship Child Health, Te Toka Tumai Auckland
1 trialPhase 3600 people
Centre Hospitalier Universitaire de Saint Etienne
1 trialPhase 2334 people
ECOG-ACRIN Cancer Research Group
1 trialPhase 25 people
Funding
1 grant since 2019American Heart AssociationUS$245.5k
Latest
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