Low birth weight

1. Low birth weight induces epigenetic regulation of gene expression in humans.

   “LBW induces epigenetic alterations during foetal development, impacting long-term health outcomes, including the early onset of sarcopenia.”

   Review

   The effect of low birth weight as an intrauterine exposure on the early onset of sarcopenia through possible molecular pathways

   Journal of cachexia, sarcopenia and muscle·29 Mar 2024

More on Epigenetic regulation of gene expression

1. Low birth weight decreases grip strength in humans.

   “LBW correlates with reduced muscle mass, grip strength, and lean body mass in adulthood”

   Review

   The effect of low birth weight as an intrauterine exposure on the early onset of sarcopenia through possible molecular pathways

   Journal of cachexia, sarcopenia and muscle·29 Mar 2024

1. Low birth weight raises the risk of heart failure in humans (HR 1.26, 95% CI [1.17, 1.36]).

   “individuals with low birth weight was associated with a 26% higher risk of heart failure (HR 1.26, 95% CI [1.17, 1.36], I2 = 2%, p < 0.00001)”

   Reviewcompared to those with normal birth weight

   The association between birth weight and incidence of heart failure in adults: a systematic review and meta-analysis

   Future cardiology·5 Dec 2025

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1. Low birth weight raises the risk of sarcopenia in humans.

   “LBW correlates with reduced muscle mass, grip strength, and lean body mass in adulthood, increasing the risk of sarcopenia.”

   Review

   The effect of low birth weight as an intrauterine exposure on the early onset of sarcopenia through possible molecular pathways

   Journal of cachexia, sarcopenia and muscle·29 Mar 2024

More on Sarcopenia