KH3

1. KH3 decreases tubular injury in humans.

   “Pharmacologic disruption of HuR-RNA interactions with the small molecule inhibitor KH3 attenuated tubular injury, inflammation, senescence, and fibrosis in aristolochic acid-induced nephropathy.”

   Animalsaristolochic acid-induced nephropathykidney tubule

   Pharmacologic disruption of HuR-RNA interactions prevents maladaptive tubular repair and AKI-to-CKD progression

   American journal of physiology. Renal physiology·29 May 2026

1. KH3 is associated with ferroptosis-associated proteins in human cells.

   “and normalized ferroptosis-associated proteins in AA-treated human proximal tubular cells.”

   Cellsaristolochic acid-treated cellsproximal tubular cell

   Pharmacologic disruption of HuR-RNA interactions prevents maladaptive tubular repair and AKI-to-CKD progression

   American journal of physiology. Renal physiology·29 May 2026

More on Ferroptosis-associated proteins