Lipid peroxidation
Biomarker2 papers1 finding
- Animals1
Interventions
1Ascorbic acid
downin reviews1
1 study
Ascorbic acid
downin reviews1
Ascorbic acid decreases lipid peroxidation.
Reviewvia ACSL4 inhibition
Ferro-aging: iron-lipid axis in systemic decline · Trends in endocrinology and metabolism: TEM · 2 Oct 2026
Latest
8Rapamycin reduces ferroptotic stress and shrinks atherosclerotic plaques in mice
The mTOR inhibitor restored macrophage efferocytosis and mitochondrial function while lowering aortic lipid burden in high-fat-fed ApoE-deficient mice.
Melissic acid reduces senescence in human stem cells via cAMP signaling
A screen of 800 natural compounds identified a phytochemical that activates autophagy and restores cell-cycle activity in models of cellular exhaustion.
Fruit flies provide an in vivo model to study ferroptosis and lifespan
Ferroptosis-inducing compounds shortened fly lifespan in a diet-dependent manner, while antioxidant treatment restored longevity and reversed iron-related changes in males.
Lack of dietary DHA drives harmful lipid remodeling and retinal degeneration in mice
Restoring the fatty acid reversed visual decline in mice and cleared toxic oxidized lipids that otherwise trigger chronic microglial activation.