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MechanismsReview

Estrogen signaling and ferroptosis in intervertebral disc degeneration: A proposed mechanistic framework and its evidence gaps

Tissue & Cell

  • Estradiol
  • Estrogen replacement therapy
  • Ferroptosis
  • Extracellular matrix remodelling
  • Intervertebral disc degeneration
  • DHODH

The paper

Yang Y, Chen C, Wu G et al.

Tissue & Cell · 22 Aug 2026

doi.org/10.1016/j.tice.2026.103892PubMed 42659810

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