Epidermal growth factor

1. Epidermal growth factor increases cell proliferation in O. cuniculus cells.

   “Further enhancement to ROCKi-containing media with EGF or STO-CM promoted sustained proliferation of rbVFEs.”

   Cellsin ROCKi-containing mediavocal fold epithelium

   Mechanotransduction-Mediated Expansion of Rabbit Vocal Fold Epithelial Cells via ROCK Inhibition and Stromal Cell-Derived Paracrine Signals

   Cells·9 Sep 2025

1. Epidermal growth factor has no effect on cellular senescence in mouse cells.

   “but had no effect on HSC senescence.”

   Cellshematopoietic stem cells

   Epidermal growth factor augments the self-renewal capacity of aged hematopoietic stem cells

   iScience·19 Jun 2024

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1. Epidermal growth factor decreases DNA damage in mouse cells.

   “EGF treatment decreased DNA damage in aged HSCs”

   Cellshematopoietic stem cells

   Epidermal growth factor augments the self-renewal capacity of aged hematopoietic stem cells

   iScience·19 Jun 2024

More on DNA damage

1. Epidermal growth factor increases hematopoietic stem cell self-renewal capacity in mice.

   “systemic administration of EGF to aged mice increased HSC self-renewal capacity in primary and secondary transplantation assays.”

   Animalssystemic EGF administration; primary and secondary transplantation assayshematopoietic stem cells

   Epidermal growth factor augments the self-renewal capacity of aged hematopoietic stem cells

   iScience·19 Jun 2024

1. Epidermal growth factor increases hematopoietic stem cell repopulation in mice.

   “increased HSC repopulation in primary and secondary transplantation assays.”

   AnimalsEGF-treated cultured HSCs evaluated in primary and secondary transplantation assaysbone marrow hematopoietic stem cells

   Epidermal growth factor augments the self-renewal capacity of aged hematopoietic stem cells

   iScience·19 Jun 2024

1. Epidermal growth factor activates cell cycle regulation.

   “effects of epidermal growth factor (EGF) to promote in vitro proliferation of neuroglia, astrocytes and oligodendrocytes.”

   Reviewneuroglia

   The ageing phenome: caloric restriction and hormones promote neural cell survival, growth, and de-differentiation

   Mechanisms of ageing and development·1 Jan 2005

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1. Epidermal growth factor increases glutamine synthetase in mouse cells.

   “MACH cultures at passage 35 responded to treatment with NGF and EGF with a dose-dependent increase in GS activity by both neurotrophins.”

   Cellspassage 35

   Plasticity of astrocytes derived from aged mouse cerebral hemispheres: changes with cell passage and immortalization

   Brain research bulletin·1 Jan 1996

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