Deoxycholic acid

  • 1 lab in 1 country
  • Funders: Japan Science and Technology Agency and 4 more
  • Animals1

Outcomes

1

Senescence-associated secretory phenotype (SASP)

upin mice1

1 study
  1. Deoxycholic acid induces senescence-associated secretory phenotype (SASP) in mice.

    “The enterohepatic circulation of DCA provokes SASP phenotype in hepatic stellate cells (HSCs)”

    Animalsvia enterohepatic circulation

    Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

    Nature26 Jun 2013

More on Senescence-associated secretory phenotype (SASP)

Funding

1 grant since 2023

Veterans Affairs

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 0Sep 2026: 1Oct 2026: 02 in 12 months
Biomedicines

Plasma metabolites link to T-cell senescence in elderly COVID-19

In elderly COVID-19 patients, altered phospholipid and bile acid metabolites tracked with T-cell senescence, inflammatory cytokines, and 180-day mortality.In elderly COVID-19 patients, altered phospholipid and bile acid metabolites tracked with T-cell senescence, inflammatory cytokines, and 180-day mortality.

Cohort study in peopleCellular senescence