Lipoma

There are 4 papers on lipoma in aging research: 1 observational study in people, 1 in animals, 2 in cells. The newest story, Nov 5, 2026: “Rare gene variants linked to benign fat and uterine tumors”.

Disease

4 papers study it1 more mentions it3 findings

MeSH

1 new paper in 30 daysSee all 5 papers on lipoma

“Lipoma risk was increased in TERF1 (odds ratio [OR], 3.32; P = 8.4 x10-), POT1, and TERF2IP carriers”
Germline Shelterin Loss of Function Predisposes to Lipoma and Uterine Leiomyoma: Population Evidence Bearing on Shelterin-Associated Sarcoma RiskmedRxiv2026doi:10.64898/2026.11.03.26367209
  • Humans1
  • Animals1
  • Cells2

Associations

3

TERF2IP

upin humans1

1 study
  1. TERF2IP is associated with lipoma in humans (germline loss-of-function variant carriers).

    “Lipoma risk was increased in TERF1 (odds ratio [OR], 3.32; P = 8.4 x10-), POT1, and TERF2IP carriers”

    Humansgermline loss-of-function variant carriers

    Rare gene variants linked to benign fat and uterine tumors

    medRxivPreprint

More on TERF2IP

POT1

upin humans1

1 study
  1. POT1 is associated with lipoma in humans (germline loss-of-function variant carriers).

    “Lipoma risk was increased in TERF1 (odds ratio [OR], 3.32; P = 8.4 x10-), POT1, and TERF2IP carriers”

    Humansgermline loss-of-function variant carriers

    Rare gene variants linked to benign fat and uterine tumors

    medRxivPreprint

More on POT1

TERF1

upin humans1OR 3.32

1 study
  1. TERF1 is associated with lipoma in humans (germline loss-of-function variant carriers) (OR 3.32).

    “Lipoma risk was increased in TERF1 (odds ratio [OR], 3.32; P = 8.4 x10-), POT1, and TERF2IP carriers”

    Humansgermline loss-of-function variant carriers

    Rare gene variants linked to benign fat and uterine tumors

    medRxivPreprint

More on TERF1

Trial sponsors

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 11 paper in 12 months
medRxiv

Rare gene variants linked to benign fat and uterine tumors

People carrying disabling variants in TERF1, a chromosome-protection gene, had 3.32 times the odds of benign fatty tumors compared with people without those variants.People carrying disabling variants in TERF1, a chromosome-protection gene, had 3.32 times the odds of benign fatty tumors compared with people without those variants.

Preprint: genetic association studyPopulations