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Cyclo

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Fundamental Research Funds for the Central Universities and 2 more
  • Animals1

Outcomes

1

Atherosclerosis

downin mice1

1 study

  1. Cyclo decreases atherosclerosis in mice.

    “Cyclo(RGDyK)] significantly inhibited high-fat diet-induced plaque formation in the aortae of apolipoprotein E (ApoE)-/- mice”

    Animalshigh-fat diet-induced in ApoE-/- miceaorta

    Oscillatory shear stress activates integrin β3, blocking autophagic flux in endothelial cells and promoting endothelial cells senescence

    Biochimica et biophysica acta. Molecular cell research22 May 2025

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