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Clofibrate + sonlicromanol

Intervention

1 paper1 finding

PubChemPubChemChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Prinses Beatrix Spierfonds
  • Animals1

Outcomes

1

Disease phenotype

no changein mice1

1 study

  1. Clofibrate + sonlicromanol has no effect on disease phenotype in mice.

    “combining clofibrate with KH176 did not result in an additive effect on disease phenotype in Ndufs4-/- mice”

    Animalsin Ndufs4-/- mice

    Effects of clofibrate and KH176 on life span and motor function in mitochondrial complex I-deficient mice

    Biochimica et biophysica acta. Molecular basis of disease15 Feb 2020

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