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Clofibrate

Intervention

2 papers2 findings

PubChemChEBIMeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Prinses Beatrix Spierfonds
  • Animals2

Outcomes

2

Motor function

upin mice1

1 study

  1. Clofibrate improves motor function in mice.

    “Clofibrate increased lifespan and motor function of Ndufs4-/- mice”

    Animalsin Ndufs4-/- mice

    Effects of clofibrate and KH176 on life span and motor function in mitochondrial complex I-deficient mice

    Biochimica et biophysica acta. Molecular basis of disease15 Feb 2020

Lifespan

upin mice1

1 study

  1. Clofibrate extends lifespan in mice.

    “Clofibrate increased lifespan and motor function of Ndufs4-/- mice”

    Animalsin Ndufs4-/- mice

    Effects of clofibrate and KH176 on life span and motor function in mitochondrial complex I-deficient mice

    Biochimica et biophysica acta. Molecular basis of disease15 Feb 2020

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