Anthracyclines
- 1 lab in 1 country
- Funder: National University of Singapore
- Humans1
Outcomes
3Circulating endothelial cells
downin humans1
1 study
Circulating endothelial cells
downin humans1
Anthracyclines decrease circulating endothelial cells in humans.
“CECs were highest at pre-treatment and declined significantly thereafter”
Humanspost-treatment
Anthracycline-mediated cardiac dysfunction: An endothelial perspective
medRxiv4 Mar 2026Preprint
Endothelial progenitor cells
downin humans1
1 study
Endothelial progenitor cells
downin humans1
Anthracyclines decrease endothelial progenitor cells in humans.
“EPCs were also highest at pre-treatment and decreased to levels below healthy controls during remission”
Humanschildhood cancer remission
Anthracycline-mediated cardiac dysfunction: An endothelial perspective
medRxiv4 Mar 2026Preprint
Cellular senescence
upin humans1
1 study
Cellular senescence
upin humans1
Anthracyclines increase cellular senescence in humans.
“EPCs were predominantly senescent up to 1-year post-treatment.”
Humanschildhood cancer remissionup to 1-year post-treatment
Anthracycline-mediated cardiac dysfunction: An endothelial perspective
medRxiv4 Mar 2026Preprint
Latest
1 in 12 monthsmedRxiv
Anthracycline-mediated cardiac dysfunction: An endothelial perspective
Preprint: cohort study in peopleMechanisms