Cardiotoxicity
Disease3 papers1 findingMeSH D066126
- Animals3
Interventions
1Exercise
downin mice1
1 study
Exercise
downin mice1
Exercise protects against cardiotoxicity in mice.
Animalsdoxorubicin treatmentheart
Exercise protects mouse hearts from chemotherapy toxicity by suppressing cellular senescence · Research Square · 29 Sep 2026 · Preprint
Latest
4Exercise protects mouse hearts from chemotherapy toxicity by suppressing cellular senescence
Physical activity preserved cardiac function and sustained FNDC5 and irisin signaling in mice exposed to doxorubicin.
Research Square · Jeyabal P et al.
Arsenic triggers heart senescence in mice while quercetin counteracts the damage
Exposure to environmental arsenic caused heart dysfunction via the p53 and p21 pathway, which quercetin treatment reversed in cultured rat cardiomyoblasts.
Toxicology and applied pharmacology · Wang H et al.
CD47 blockade reduces doxorubicin-induced cardiac aging in male mice
Inhibiting CD47 lessens heart dysfunction and blunts cellular senescence caused by the chemotherapy drug doxorubicin.
Physiological reports · Yan A et al.