STRA6

1. STRA6 induces senescence-associated secretory phenotype (SASP).

   “establishing a senescence-associated secretory phenotype (SASP).”

   Reviewvia JAK/STAT and NLRP3 inflammasome crosstalk

   Beyond a gatekeeper: the non-classical signaling role of STRA6 in driving endothelial senescence and atherosclerosis

   Frontiers in immunology·17 Feb 2026

More on Senescence-associated secretory phenotype (SASP)

1. STRA6 activates JAK–STAT signalling.

   “STRA6 activation of the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway.”

   Reviewvia non-classical signaling in metabolic disease

   Beyond a gatekeeper: the non-classical signaling role of STRA6 in driving endothelial senescence and atherosclerosis

   Frontiers in immunology·17 Feb 2026

More on JAK–STAT signalling

1. STRA6 raises the risk of atherosclerosis.

   “Beyond a gatekeeper: the non-classical signaling role of STRA6 in driving endothelial senescence and atherosclerosis”

   Reviewvia RBP4-STRA6 signaling axis in endothelium

   Beyond a gatekeeper: the non-classical signaling role of STRA6 in driving endothelial senescence and atherosclerosis

   Frontiers in immunology·17 Feb 2026

More on Atherosclerosis