SPART

SPART protects against osteoporosis-like phenotype in mice.

“Conditional deletion of Spart in MSCs reproduced an osteoporosis-like phenotype in young mice.”

Animalsshown by conditional deletion of Spart in MSCsbone-marrow mesenchymal stem cells

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·27 Apr 2026