Sirt3
GeneMus musculus3 papers1 findingMGI 1927665NCBI Gene 64384Taxon 10090
- Animals3
Interventions
1Inotodiol
upin mouse cells1
1 study
Inotodiol
upin mouse cells1
Inotodiol increases Sirt3 in mouse cells.
Cells
Inotodiol preserves muscle mass and function in aged mice · Signal transduction and targeted therapy · 25 Sep 2026
Latest
3Astragaloside IV reduces cardiac aging in mice by restoring mitochondrial balance
The compound lowered senescence markers and improved heart function through SIRT3-driven DRP1 deacetylation in aged mice and cultured cardiomyocytes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · Chen X et al.
Hallmarks of Aging Associate with High Intensity Interval Training Benefits and Frailty in Female C57Bl/6J Mice
AnimalsThe journals of gerontology. Series A, Biological sciences and medical sciences
Inotodiol preserves muscle mass and function in aged mice
The mycosterol restores mitochondrial metabolism by activating the LXRbeta-SIRT3-PGC-1alpha pathway to counter age-related muscle decline.
Signal transduction and targeted therapy · You CL et al.