Il1b
GeneMus musculus5 papersMGI 96543NCBI Gene 16176Taxon 10090
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5Gastrodia elata polysaccharide extends worm lifespan and mitigates age-related deficits in mice
The treatment reduced oxidative stress, suppressed inflammation, and remodeled the gut microbiome in naturally aging mice while prolonging survival in nematodes.
Food science & nutrition · Shi H et al.
Icariin improves cognition and reduces neuroinflammation by promoting mitophagy in mice
The flavonoid engages PINK1 to curb microglial pyroptosis and mitochondrial stress in models of Alzheimer's disease.
Chinese journal of natural medicines · Fan L et al.
Astragaloside IV reduces cardiac aging in mice by restoring mitochondrial balance
The compound lowered senescence markers and improved heart function through SIRT3-driven DRP1 deacetylation in aged mice and cultured cardiomyocytes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · Chen X et al.
Alda-1 Alleviates the Cognitive Deficits in D-galactose-induced Aging Mice by Regulating Oxidative Stress, Neuroinflammation, and Mitochondrial Biogenesis
Lack of the AT2R receptor accelerates cardiac senescence and fibrosis in aging mice
Mice lacking the receptor also showed higher inflammation, elevated DNA damage, and a five-month reduction in median lifespan.
Clinical science (London, England : 1979) · Zacarias-Rodrigues LM et al.