SDHAF4
Gene1 paper1 findingHGNC 20957MGI 1915252NCBI Gene 135154Taxon 9606
- Animals1
Interventions
1Intermittent fasting
downin mice1
1 study
Intermittent fasting
downin mice1
Intermittent fasting decreases SDHAF4 in mice.
“Mechanistically, ADF downregulates the mitochondrial chaperone SDHAF4, thereby suspending complex II assembly and promoting eNOS-derived nitric oxide (NO) production.”
Animalsalternate-day fastinghepatocyte
Alternate-day fasting resolves liver fibrosis via hepatocyte eNOS signaling · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Latest
1Advanced ScienceAnimals
Alternate-day fasting resolves liver fibrosis via hepatocyte eNOS signaling
Nitric oxide produced by hepatocytes during fasting blocks autophagy in stellate cells to halt fibrotic progression in mice.Nitric oxide produced by hepatocytes during fasting blocks autophagy in stellate cells to halt fibrotic progression in mice.