SCAF1
Gene1 paper2 findingsHGNC 30403NCBI Gene 58506Taxon 9606
- Cells1
Effects
2Cellular senescence
upin human cells1
1 study
Cellular senescence
upin human cells1
SCAF1 induces cellular senescence in human cells.
Cellsoverexpressionfibroblast
Peroxisomal stress drives cellular senescence by relocating SCAF1 to mitochondria · bioRxiv : the preprint server for biology · 23 Sep 2026 · Preprint
Mitochondrial translation
downin human cells1
1 study
Mitochondrial translation
downin human cells1
SCAF1 inhibits mitochondrial translation in human cells.
Cellsunder peroxisome stress
Peroxisomal stress drives cellular senescence by relocating SCAF1 to mitochondria · bioRxiv : the preprint server for biology · 23 Sep 2026 · Preprint
Latest
1Peroxisomal stress drives cellular senescence by relocating SCAF1 to mitochondria
Processed SCAF1 halts mitochondrial ribosome assembly and induces senescence in human cell models following peroxisome import stress.Processed SCAF1 halts mitochondrial ribosome assembly and induces senescence in human cell models following peroxisome import stress.