NAMPT
GeneHomo sapiens2 papers1 findingHGNC 30092NCBI Gene 10135Taxon 9606
- Cells2
Effects
1BMAL1
is required forin human cells1
1 study
BMAL1
is required forin human cells1
NAMPT is required for BMAL1 in human cells.
Cellsfor AICAR-induced Bmal1 promoter modulationU2OS
AMPK lengthens the circadian clock period through NAD+-dependent regulation of Bmal1 · bioRxiv · 30 Sep 2026 · Preprint
Latest
2AMPK lengthens the circadian clock period through NAD+-dependent regulation of Bmal1
Experiments in human cells and computational modeling show that fasting sensor AMPK requires NAD+ and PGC-1-alpha to modulate cellular circadian rhythms.
bioRxiv · Vandenberghe A et al.
Mechanism of the NAMPT-SIRT2-Lactate Axis in Senescence of Human Nucleus Pulposus Cells
CellsFrontiers in bioscience (Landmark edition)