Aicar
Intervention1 paper1 findingPubChem 65110ChEBI 18406
- Cells1
Outcomes
1BMAL1
upin human cells1
1 study
BMAL1
upin human cells1
Aicar increases BMAL1 in human cells.
CellsU2OS
AMPK lengthens the circadian clock period through NAD+-dependent regulation of Bmal1 · bioRxiv · 30 Sep 2026 · Preprint
Latest
1AMPK lengthens the circadian clock period through NAD+-dependent regulation of Bmal1
Experiments in human cells and computational modeling show that fasting sensor AMPK requires NAD+ and PGC-1-alpha to modulate cellular circadian rhythms.