Lactate

Biomarker3 papers1 finding

Animals1
Cells1

Interventions

Nampt knockdown

downin human cells1

1 study

Nampt knockdown decreases lactate in human cells.
CellssiRNAnucleus pulposus cell
Mechanism of the NAMPT-SIRT2-Lactate Axis in Senescence of Human Nucleus Pulposus Cells · Frontiers in bioscience (Landmark edition) · 1 Sep 2026

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AnimalsPeer-reviewedCellular senescence38 min

Jianwei Shoutai Pills reduce uterine aging and pregnancy loss in aged mice

The herbal formula delayed thymic involution, restored regulatory T cell function, and improved maternal-fetal immune tolerance by altering metabolic signaling in aging female mice.

Phytomedicine : international journal of phytotherapy and phytopharmacology · Guan F et al.

Paper

Pulsed Reductive Impulses via Donor Addition or Acceptor Subtraction: A Novel Paradigm for Anti-Cancer and Anti-Aging Metabolic Therapy

ReviewPreprintPreprints.org2 h

Muscle-brain crosstalk in sarcopenia and cognitive impairment: endocrine signaling, metabolic regulation, and exercise modulation

ReviewFrontiers in endocrinologyYesterday

Pulsed Reductive Impulses via Exogenous Reducing Equivalents: A Novel Paradigm for Anti-Cancer and Anti-Aging Metabolic Therapy

ReviewPreprintPreprints.org30 Sep

Mechanism of the NAMPT-SIRT2-Lactate Axis in Senescence of Human Nucleus Pulposus Cells

CellsFrontiers in bioscience (Landmark edition)30 Sep

AnimalsPreprintCellular senescence26 Sep

Lactate receptor activation reduces cellular senescence and protects vascular health in mice

Loss of the lactate receptor GPR81 drives arterial senescence and lipid accumulation, while pharmacological stimulation restores vascular homeostasis in progeroid mice.

bioRxiv · Wu Y et al.

Paper