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USP-48 modulates mitochondrial stress and enables longevity in low-insulin worms

A genome-wide screen in roundworms links histone H2B deubiquitination by USP-48 to mitochondrial stress signaling and extended lifespan.A genome-wide screen in roundworms links histone H2B deubiquitination by USP-48 to mitochondrial stress signaling and extended lifespan.