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bcat-1

Gene

3 papers3 findings

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Glenn Family Foundation and 6 more
  • Model organisms3

Effects

3

Reproduction

upin worms1

1 study

  1. bcat-1 improves reproduction in worms.

    “reproduction can be extended in wild-type animals both by bcat-1 overexpression and by supplementing with vitamin B1”

    Model organismsin wild-type animals

    Enhanced branched-chain amino acid metabolism improves age-related reproduction in C. elegans

    Nature metabolism28 Feb 2024

Oocyte quality

downin worms1

1 study

  1. bcat-1 decreases oocyte quality in worms.

    “bcat-1 knockdown decreases oocyte quality in daf-2 worms and reduces reproductive capability”

    Model organismsin daf-2 mutant worms

    Enhanced branched-chain amino acid metabolism improves age-related reproduction in C. elegans

    Nature metabolism28 Feb 2024

More on Oocyte quality

Oocyte quality

upin worms1

1 study

  1. bcat-1 improves oocyte quality in worms.

    “bcat-1 knockdown decreases oocyte quality in daf-2 worms and reduces reproductive capability”

    Model organismsin daf-2 mutants

    Enhanced Branched-Chain Amino Acid Metabolism Improves Age-Related Reproduction in C. elegans

    bioRxiv : the preprint server for biology9 Feb 2024Preprint

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