Thiamine

3 papers4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

3 independent labs in 2 countries

Humans2

Outcomes

Cognitive function

upin humans1

1 study

Thiamine improves cognitive function in humans.
Human trialin a patient with acute nutritional axonal neuropathy and vitamin deficiencies following semaglutide therapy5 daysfemalesn = 1
Acute Nutritional Axonal Neuropathy in the Setting of Semaglutide-Associated Gastrointestinal Intolerance: A Case Report
Case reports in neurology16 Jun 2026

Limb strength

upin humans1

1 study

Thiamine improves limb strength in humans.
Human trialin a patient with acute nutritional axonal neuropathy and vitamin deficiencies following semaglutide therapy5 daysfemalesn = 1
Acute Nutritional Axonal Neuropathy in the Setting of Semaglutide-Associated Gastrointestinal Intolerance: A Case Report
Case reports in neurology16 Jun 2026