There are 4 papers on ALMS1 in aging research: none in people yet, 1 in animals, 2 in cells. The newest story, Nov 2, 2026: “A protein helps cells build and maintain tiny projections”.
1 new paper in 30 daysSee all 4
Cilia loss
downin mice1
ALMS1 prevents cilia loss in mice (shown by ALMS1 disruption; progressive and age-dependent).
“In mice, disruption of ALMS1 causes progressive, age-dependent loss of cilia in tissues affected in Alström syndrome, including retina, kidney, and brain.”
Animalsshown by ALMS1 disruption; progressive and age-dependentretina, kidney, and brain
A protein helps cells build and maintain tiny projections
The Journal of cell biology
Cells lacking the protein ALMS1 had short, frequently broken centrioles, structures that help build cilia, the tiny projections on cell surfaces.Cells lacking the protein ALMS1 had short, frequently broken centrioles, structures that help build cilia, the tiny projections on cell surfaces.