Alström syndrome

Disease1 paper2 findings

  • Humans1

Effects

2

IMM-AGE

upin humans1

1 study

  1. Alström syndrome increases IMM-AGE in humans.

    Humansin PBMCs relative to chronological age compared to matched controlsperipheral blood mononuclear celln = 10

    SUN-648 Monogenic Syndromic Obesity of Alström Syndrome as a Model of Premature Aging · ENDO 2025 abstract · 22 Oct 2025

IMM-AGE →

Senescence-associated beta-galactosidase

upin humans1

1 study

  1. Alström syndrome increases senescence-associated beta-galactosidase in humans (55.4 ± 11.3-fold).

    Humansin adipocytes compared to matched controlsadipocyten = 10

    SUN-648 Monogenic Syndromic Obesity of Alström Syndrome as a Model of Premature Aging · ENDO 2025 abstract · 22 Oct 2025

Senescence-associated beta-galactosidase →

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