Spine-and-hip fractures

Disease1 paper1 finding

  • Humans1

Associations

1

GIPR

downin humans1OR 0.68

1 study
  1. GIPR lowers the risk of spine-and-hip fractures in humans (OR 0.68, 95% CI 0.49-0.94).

    Humansscaled to lower BMI

    Genetically proxied GIP pathway links to lower fracture risk · Diabetes, obesity & metabolism · 29 Sep 2026

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Diabetes, Obesity & MetabolismHumans

Genetically proxied GIP pathway links to lower fracture risk

Scaled to lower BMI, genetically proxied GIP-GIPR perturbation tracked with lower odds of major osteoporotic fractures (OR 0.80) and spine-and-hip…Scaled to lower BMI, genetically proxied GIP-GIPR perturbation tracked with lower odds of major osteoporotic fractures (OR 0.80) and spine-and-hip fractures (OR 0.68).