Estimated bone mineral density
Biomarker1 paper1 finding
- Humans1
Upstream
1GLP-1 and incretin signalling
no changein humans1
1 study
GLP-1 and incretin signalling
no changein humans1
GLP-1 and incretin signalling has no effect on estimated bone mineral density in humans.
Humans
Genetically proxied GIP pathway links to lower fracture risk · Diabetes, obesity & metabolism · 29 Sep 2026
Latest
2Cortical surface areas link to fall-related fracture odds
Larger caudal anterior cingulate area linked to lower simple-fall fracture odds (OR 0.95), while larger insula area linked to higher odds (OR 1.05).Larger caudal anterior cingulate area linked to lower simple-fall fracture odds (OR 0.95), while larger insula area linked to higher odds (OR 1.05).
Genetically proxied GIP pathway links to lower fracture risk
Scaled to lower BMI, genetically proxied GIP-GIPR perturbation tracked with lower odds of major osteoporotic fractures (OR 0.80) and spine-and-hip…Scaled to lower BMI, genetically proxied GIP-GIPR perturbation tracked with lower odds of major osteoporotic fractures (OR 0.80) and spine-and-hip fractures (OR 0.68).