Parkinsonism

Disease

3 papers5 findings

  • Humans2

Interventions

1

Dash diet

no changein humans1

1 study
  1. Dash diet has no effect on parkinsonism in humans.

    Humans4.6 yearsn = 706

    MIND Diet Associated with Reduced Incidence and Delayed Progression of ParkinsonismA in Old Age

    The journal of nutrition, health & aging1 Jan 2018

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Associations

4

Hip fracture

upin humans1HR 1.42

1 study
  1. Parkinsonism raises the risk of hip fracture in humans (HR 1.42, 95% CI 1.19-1.70).

    Humansfollowing fall-related hospitalization2 yearsn = 88,140

    Factors associated with hip fracture following a fall-associated hospitalization in older adults: a retrospective cohort study

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA8 Aug 2026

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Mind diet

downin humans1HR 0.89

1 study
  1. Mind diet lowers the risk of parkinsonism in humans (HR 0.89, 95% CI 0.83-0.96).

    Humans4.6 yearsn = 706

    MIND Diet Associated with Reduced Incidence and Delayed Progression of ParkinsonismA in Old Age

    The journal of nutrition, health & aging1 Jan 2018

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IL-6

upin humans1

1 study
  1. Parkinsonism is associated with IL-6 in humans (28 (-3, 69)%).

    Humansserum

    Association of circulating TNF-alpha and IL-6 with ageing and parkinsonism

    Acta neurologica Scandinavica1 Jul 1999

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TNF-alpha

upin humans1

1 study
  1. Parkinsonism is associated with TNF-alpha in humans.

    Humansin parkinsonians with abnormal postural and psychomotor responsesserum

    Association of circulating TNF-alpha and IL-6 with ageing and parkinsonism

    Acta neurologica Scandinavica1 Jul 1999

More on TNF-alpha

Trial sponsors

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Research Square

Alpha-synuclein pathology alters lipids in mice and human cells

In mouse midbrain and cultured human neurons, alpha-synuclein pathology led to shorter, more saturated lipid chains, an effect largely reversed in mice by intermittent…In mouse midbrain and cultured human neurons, alpha-synuclein pathology led to shorter, more saturated lipid chains, an effect largely reversed in mice by intermittent fasting.

Preprint: experiments in miceMechanisms
International Journal of Obesity

Weight-loss surgery linked to lower dementia and Parkinson's risk

Rates of dementia and Parkinson's disease were lower after surgery, with hazard ratios of 0.48 and 0.70 compared with matched people without surgery.Rates of dementia and Parkinson's disease were lower after surgery, with hazard ratios of 0.48 and 0.70 compared with matched people without surgery.

Cohort study in peopleParkinson's disease
JMIR Aging

AI detects cognitive concerns in older adults with normal tests

In an observational study, 13.8% of older adults with normal cognitive test scores had memory or thinking concerns documented in their health records.In an observational study, 13.8% of older adults with normal cognitive test scores had memory or thinking concerns documented in their health records.

Cohort study of 15,750 peopleBiomarkers