In one genetic group, each extra diet-score point was linked to lower relative Alzheimer’s dementia risk over time (hazard ratio 0.82).In one genetic group, each extra diet-score point was linked to lower relative Alzheimer’s dementia risk over time (hazard ratio 0.82).
Researchers identified three vessel states across disease severity by analysing 11,409 vessel fragments from post-mortem brain tissue from 20 cases.Researchers identified three vessel states across disease severity by analysing 11,409 vessel fragments from post-mortem brain tissue from 20 cases.
A measure of prediction performance rose from 0.79 for symptoms alone to 0.90 when blood biomarkers were added.A measure of prediction performance rose from 0.79 for symptoms alone to 0.90 when blood biomarkers were added.
In six-month-old mice with accelerated aging, ER272 was linked to better cognition and preserved markers of new brain cells in males, but showed limited effects in…In six-month-old mice with accelerated aging, ER272 was linked to better cognition and preserved markers of new brain cells in males, but showed limited effects in females.
Brain donors with early-life farming exposure had 60% higher odds of Alzheimer's disease neuropathology than those without such exposure.Brain donors with early-life farming exposure had 60% higher odds of Alzheimer's disease neuropathology than those without such exposure.
A two-year randomised trial in 1,260 older adults at risk of dementia found no clear evidence that starting blood markers altered cognitive benefits.A two-year randomised trial in 1,260 older adults at risk of dementia found no clear evidence that starting blood markers altered cognitive benefits.