CRMP2 isoaspartyl sites

1. In vitro aging increases CRMP2 isoaspartyl sites in mouse cells.

   “In vitro aging of rCRMP2 at pH 7.4, 37°C for 0-28 days led to robust accumulation of isoAsp sites that were repairable by PIMT”

   Cellscell-free in vitro aging at pH 7.4 and 37°Cpurified recombinant mouse CRMP20–28 days

   Isoaspartate formation and irreversible aggregation of collapsin response mediator protein 2: implications for the etiology of epilepsy and age-related cognitive decline

   Research square·14 Nov 2024Preprint

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