PCMT1

Gene

2 papers1 finding

HGNCNCBI GeneTaxon

  • 1 lab
  • Funder: American Heart Association
  • Animals2

Effects

1

CRMP2 isoaspartyl damage

downin mouse cells1

1 study
  1. PCMT1 decreases CRMP2 isoaspartyl damage in mouse cells.

    “led to robust accumulation of isoAsp sites that were repairable by PIMT”

    Cellscell-free in vitro aging at pH 7.4 and 37°Cpurified recombinant mouse CRMP20–28 days

    Isoaspartate formation and irreversible aggregation of collapsin response mediator protein 2: implications for the etiology of epilepsy and age-related cognitive decline

    Research square14 Nov 2024Preprint

Funding

1 grant since 2016

American Heart AssociationUS$400k

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