Keloid

1. Keloid increases mesenchymal fibroblasts in humans.

   “notably, mesenchymal fibroblasts were predominantly increased in keloids.”

   Humansin keloidskeloid

   Single-cell RNA-seq reveals increased TNFRSF9⁺ senescent fibroblasts and enhanced crosstalk between TNFRSF9⁺ fibroblasts and neural cells in keloids

   Burns : journal of the International Society for Burn Injuries·11 May 2026

1. PhenoAge lowers the risk of keloid in silico.

   “whereas PhenoAge exhibited negative correlations”

   In silicogenetic association (MR)

   Deciphering the Causal Links Among Metabolomics, Ageing Phenotypes, and Pathological Scars: A Two-Sample Mendelian Randomization Study

   Clinical, cosmetic and investigational dermatology·11 May 2026

More on PhenoAge

1. Telomere length raises the risk of keloid in silico.

   “telomere length showed positive correlations with both scar types”

   In silicogenetic association (MR)

   Deciphering the Causal Links Among Metabolomics, Ageing Phenotypes, and Pathological Scars: A Two-Sample Mendelian Randomization Study

   Clinical, cosmetic and investigational dermatology·11 May 2026

More on Telomere length

1. Cellular senescence is associated with keloid in humans.

   “senescence-resumed proliferation (SRP) and keloid recurrence and treatment resistance”

   Reviewin keloid pathology

   Cellular Senescence in Keloid Pathology: Mechanisms, Biomarkers, and Potential Therapeutic Targets

   Biomedicines·16 Apr 2026

More on Cellular senescence