CA9

1. CA9 decreases cell proliferation in human cells.

   “decreased proliferation”

   CellsCA9 overexpressionkeloid fibroblasts

   CA9-Positive Keloid Fibroblasts: Modulator of Local Inflammation Induced by the Hypoxic and Glycolysis-enhanced Microenvironment

   Anticancer research·28 May 2025

1. CA9 increases inflammation in human cells.

   “increased expression of inflammatory factors”

   CellsCA9 overexpressionkeloid fibroblasts

   CA9-Positive Keloid Fibroblasts: Modulator of Local Inflammation Induced by the Hypoxic and Glycolysis-enhanced Microenvironment

   Anticancer research·28 May 2025

More on Inflammation

1. CA9 induces cellular senescence in human cells.

   “CA9-overexpressing KFs presented features of senescent cells, including increased senescence-associated β-galactosidase activity”

   CellsCA9 overexpressionkeloid fibroblasts

   CA9-Positive Keloid Fibroblasts: Modulator of Local Inflammation Induced by the Hypoxic and Glycolysis-enhanced Microenvironment

   Anticancer research·28 May 2025

More on Cellular senescence

1. Keloid is associated with CA9 in humans.

   “HIF-1α, Glut-1, and CA9 expression were higher in keloid tissues than in normal skin tissue samples”

   Humanskeloid vs normal skin tissueskin

   CA9-Positive Keloid Fibroblasts: Modulator of Local Inflammation Induced by the Hypoxic and Glycolysis-enhanced Microenvironment

   Anticancer research·28 May 2025

More on Keloid