Infantile neuronal ceroid lipofuscinosis

3 papers

Animals3

Latest

PNAS3 Jul

Synergistic effects of treating the spinal cord and brain in CLN1 disease

Experiments in miceInterventions

Molecular Therapy26 Dec

Effective intravenous therapy for neurodegenerative disease with a therapeutic enzyme and a peptide that mediates delivery to the brain

Experiments in miceInterventions

Nature Neuroscience22 Sep

Neuroprotection and lifespan extension in Ppt1(-/-) mice by NtBuHA: therapeutic implications for INCL

Experiments in miceInterventions

Annals of Neurology24 Feb

Synergistic effects of central nervous system-directed gene therapy and bone marrow transplantation in the murine model of infantile neuronal ceroid lipofuscinosis

Experiments in miceInterventions

Human Molecular Genetics28 Dec

Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: partial rescue by resveratrol

Experiments in miceResveratrol