Bone degeneration

2 papers

Animals1

Latest

7 in 12 months

Biogerontology12 Aug

Isoorientin attenuates aging-induced bone deterioration by suppressing M1-mediated TLR4-MAPK-NF-κB inflammatory signaling

Experiments in miceBones and joints

Osteoporosis International10 Mar

Molecular-level understanding of the aging bone and regeneration mechanisms using computational methods

ReviewBones and joints

Journal of Orthopaedic Translation27 Feb

Endothelin-1/endothelin B receptor signalling mediates Prx1⁺ skeletal stem cells senescence: A driver of osteoporotic bone loss

Experiments in micePI3K–AKT signalling

Bone Research14 Feb

Smart biomaterials for skeletal aging repair and regeneration

ReviewInterventions

Life Sciences21 Jan

Hyperglycemia disrupts alveolar bone homeostasis by inducing stem cell senescence through Mettl3/Foxo3/Sirt1 axis in diabetic periodontitis

Experiments in miceSirtuin signalling

Advanced Science20 Jan

DEL-1 is an Endogenous Senolytic Protein that Inhibits Senescence-Associated Bone Loss

Experiments in miceBones and joints

Biology30 Dec

Mechanistic Study of Hypoxia-Mediated Regulation of Osteoblast Senescence via ATP6V1A-Dependent Modulation of Metabolic Remodeling

Experiments in miceHypoxia and HIF signalling

Frontiers in Physiology16 Dec

Benefits and Mechanisms of Exercise Training for Knee Osteoarthritis

ReviewAerobic exercise