HK2
Gene1 paper1 findingHGNC 4923NCBI Gene 3099Taxon 9606
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.
A gene’s or a process’s line counts the gene with the processes named after it, as NLRP3 with the NLRP3 inflammasome, and the trials of drugs aimed at it.
- Animals1
Interventions
1Recombinant human APOE2
upin mouse cells1
1 study
Recombinant human APOE2
upin mouse cells1
Recombinant human APOE2 increases HK2 in mouse cells.
Cellsin ApoE4-knockin mouse primary neurons
Recombinant sialylated ApoE2 suppresses ApoE4 and sex-specifically strengthens brain metabolism and cognition in ApoE4 mice · bioRxiv : the preprint server for biology · 4 Aug 2026 · Preprint