Alcohol use disorder

Disease2 papers3 findings

  • Humans2

Effects

1

Cognitive function

downin humans1

1 study
  1. Alcohol use disorder impairs cognitive function in humans (estimate = -0.092, 95% CI [-0.173, -0.010], p = 0.03).

    Humanslifetime AUD history

    Lifetime alcohol use disorder speeds cognitive decline · medRxiv : the preprint server for health sciences · 23 Sep 2026 · Preprint

Associations

2

Vascular dementia

upin humans1

1 study
  1. Alcohol use disorder raises the risk of vascular dementia in humans (3.96 [3.44-4.56]).

    Humansfemales

    Alcohol use disorder links to higher dementia risk in women · medRxiv · 29 Sep 2026 · Preprint

Vascular dementia →

Dementia

upin humans1HR 3.73

1 study
  1. Alcohol use disorder raises the risk of dementia in humans (HR=3.73 [95% CI 3.52-3.95]).

    Humansfemales

    Alcohol use disorder links to higher dementia risk in women · medRxiv · 29 Sep 2026 · Preprint

Dementia →

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medRxivHumansPreprint

Lifetime alcohol use disorder speeds cognitive decline

In model projections, lifetime disorder added an estimated 7.1 years of cognitive aging at age 60 and 13.8 years at age 75.In model projections, lifetime disorder added an estimated 7.1 years of cognitive aging at age 60 and 13.8 years at age 75.

medRxivHumansPreprint

Alcohol use disorder links to higher dementia risk in women

Women with alcohol use disorder had a hazard ratio of 3.73 for all-cause dementia compared to controls, rising to 10.68 before age 70.Women with alcohol use disorder had a hazard ratio of 3.73 for all-cause dementia compared to controls, rising to 10.68 before age 70.