What does the research say about Wave I amplitude?

Wave I amplitude

There are 3 papers on wave I amplitude in aging research: none in people yet, 3 in animals. The newest story, Oct 4, 2026: “Auditory brainstem signals track age-related hearing deficits”.

Biomarker

3 papers study it31 more mention it

1 new paper in 30 daysSee all 34

Animals3

Latest

9 papers in 12 months

Cell Death DiscoveryJul 6

FGF13 prevents age-related hearing loss by protecting spiral ganglion neurons and ribbon synapses from injury

Experiments in miceAge-related hearing loss

Paper

International Journal of Molecular SciencesAug 8

Istradefylline Mitigates Age-Related Hearing Loss in C57BL/6J Mice

Experiments in miceAge-related hearing loss

Paper

Experimental GerontologyAug 28

Txn2 haplodeficiency does not affect cochlear antioxidant defenses or accelerate the progression of cochlear cell loss or hearing loss across the lifespan

Experiments in miceEar

Paper

bioRxivOct 9

Functional and molecular profiles of the neuroretina and retinal pigmented epithelium-choroid in response to aging and Nrf2 deletion

Preprint: experiments in miceNRF2–KEAP1 antioxidant response

Paper

bioRxivSep 27

Auditory brainstem signals track age-related hearing deficits

In normal-hearing listeners, auditory brainstem responses and behavioral detection thresholds revealed that declining Wave V amplitudes correlated with poorer temporal…In normal-hearing listeners, auditory brainstem responses and behavioral detection thresholds revealed that declining Wave V amplitudes correlated with poorer temporal processing at higher sound levels.

Preprint: cross-sectional study in peopleEar

Paper

NeuroscienceJul 29

Auditory brainstem response in the identification of cochlear synaptopathy in aged rodents: a systematic review with meta-analysis

Meta-analysis of animal and cell studiesAuditory brainstem response

Paper

International Journal of AudiologyJul 22

Comparing metrics of cochlear and auditory brainstem function in early-aged ears

Cross-sectional study of 33 peopleEar

Paper

Journal of the Association for Research in OtolaryngologyJul 1

Model reproduces altered sound responses in aging gerbils

A computer model matched electrical sound-response patterns from 23 old and 39 young gerbils and pointed to reduced activity in a brainstem region.A computer model matched electrical sound-response patterns from 23 old and 39 young gerbils and pointed to reduced activity in a brainstem region.

Computational studyAuditory brainstem response

Paper

Hearing ResearchJun 13

Interplay of age, speech perception in noise, standard and extended high-frequency hearing, and cochlear synaptopathy in individuals with normal audiograms

Cross-sectional study of 60 peopleEar

Paper

Hearing ResearchMar 30

Acute nicotine affects auditory brainstem responses in a frequency-, age-, and sex-dependent manner in mice

Experiments in miceNicotine

Paper

See all 34