VSMC senescence

3 papers

Humans1
Animals2

Latest

12 in 12 months

iScience18 Sep

MTR4 deficiency attenuates abdominal aortic aneurysm progression through suppressing VSMC senescence via the MTR4-RAP1a axis

Experiments in miceCellular senescence

Aging Cell18 Aug

AK050834 Deficiency Prevents Vascular Aging via Opposite Regulation of Two Senescence-Sensitive Genes ATF3 and p21

Experiments in miceCellular senescence

Advanced Science5 Aug

USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

Experiments in miceCellular senescence

Aging and Disease30 Mar

SIRT2 Delays Vulnerable Plaque Progression by Modulating Vascular Smooth Muscle Cell Senescence

Experiments in miceInterventions

Cellular Signalling25 Mar

Glut1-dependent lactylation drives VSMC senescence phenotype

Experiments in mouse cellsCellular senescence

FASEB Journal12 Mar

ZNF384-Driven Fibulin-1 Exacerbates Vascular Stiffness via TGF-β/Smad3-Mediated Senescence and Fibrosis

Experiments in miceCellular senescence

Biomaterials7 Mar

Engineered extracellular vesicles from human placental mesenchymal stem cells attenuate abdominal aortic aneurysm formation by inhibiting Nat10-mediated vascular smooth muscle cell senescence

Experiments in miceAbdominal aortic aneurysm

bioRxiv2 Mar

Metformin Stabilizes the Abdominal Aorta in Aneurysm by Restoring VSMC Mitochondrial Homeostasis via the AMPK–SIRT1–PGC-1α Axis

Preprint: experiments in miceMetformin

Translational Stroke Research10 Feb

Integration of Multi-Omics and Machine Learning Identifies TGFB1 and SERPINE1 as Biomarkers of Vascular Smooth Muscle Cell Senescence in Intracranial Aneurysms

Study in peopleBiomarkers

International Journal of Molecular Sciences28 Jan

Thrombospondin 1-CD47 Signalling Modulates Vascular Smooth Muscle Cell Senescence in Chronic Kidney Disease

Experiments in miceMAPK/ERK signalling