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Type I interferon signature

There are 3 papers on type I interferon signature in aging research: 1 observational study in people, 2 in animals.

Biomarker

3 papers study it1 finding

See all 3 papers on type I interferon signature

“blood-derived macrophages, whole blood and brain tissue from patients with C9-ALS/FTD all show an elevated type I interferon signature compared with samples from people with sporadic ALS/FTD”
C9orf72 in myeloid cells suppresses STING-induced inflammationNature2020doi:10.1038/s41586-020-2625-x
  • Humans1
  • Animals2

Associations

1

C9-ALS/FTD

upin humans1

1 study

  1. C9-ALS/FTD is associated with type I interferon signature in humans (compared with sporadic ALS/FTD).

    “blood-derived macrophages, whole blood and brain tissue from patients with C9-ALS/FTD all show an elevated type I interferon signature compared with samples from people with sporadic ALS/FTD”

    Humanscompared with sporadic ALS/FTDblood-derived macrophages, whole blood and brain tissue

    C9orf72 in myeloid cells suppresses STING-induced inflammation

    Nature

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