C9ORF72
Gene4 papers2 findingsHGNC 28337NCBI Gene 203228Taxon 9606
- Human trial1
- Humans3
Effects
2Thalamic volume
downin humans1
1 study
Thalamic volume
downin humans1
C9ORF72 decreases thalamic volume in humans.
Humanspremanifest C9RE carriers
Tracking Socio-emotional Brain Changes in Premanifest C9orf72 Repeat Expansion Carriers: A Structural and Functional 2-Year Longitudinal Magnetic Resonance Imaging Study · Annals of neurology · 7 Sep 2026
Emotion recognition efficiency
downin humans1
1 study
Emotion recognition efficiency
downin humans1
C9ORF72 decreases emotion recognition efficiency in humans.
Humanspremanifest C9RE carriers vs controls
Tracking Socio-emotional Brain Changes in Premanifest C9orf72 Repeat Expansion Carriers: A Structural and Functional 2-Year Longitudinal Magnetic Resonance Imaging Study · Annals of neurology · 7 Sep 2026
Funding
National Institute on AgingUS$3.7mNational Institute of Neurological Disorders and StrokeUS$701.8k2 grants since 2016
C9orf72 amyotrophic lateral sclerosis/frontotemporal dementia Prevent
National Institute on AgingUniversity of Miami School of MedicineUS$3.7m2026–2031
Molecular effects of metformin, PKR and TBI on C9orf72 ALS/FTD
National Institute of Neurological Disorders and StrokeUniversity of FloridaUS$701.8k2016–2027